Introduction

    

Macrophage Products:

Cases
   

TISSUE INJURY

Toxic O2 Radicles

Proteases

Neutrophil Chemotatic factors

Tumour Necrosis factor

Coagulation factors (V, VII & X)

A.A. metabolites

Nitric oxide

FIBROSIS

Growth factors
(PDGF, FGF, TGF-b)

Fibrinogenic cytokines

Angiogenesis factors (FGF)

“Remodelling” collagenases

    

Activated Macrophage

Review Questions

Back to Prac Classes
 

Remember macrophages produce up 100 different products in response to stimuli. Some of these products invoke the inflammatory response (tissue injury) while others coordinate the reparative response (fibrosis).