Introduction

Case 7:

History:

12 year old Golden Retriever dog with a focal, pedunculated lesion protruding from the rectum.

Colon (x40). Segmental transformation of colonic mucosa – neoplastic mucosa is darker blue due to high density of cells (green arrowhead). Non-neoplastic mucosa – some colonic glands have being distorted due to compression by tumour – producing cystic dilation of glands, filled with mucus (black arrowhead).

Slide Ref: 148/03 *

Colon (x40).

Slide Ref: 148/03 *

Colon (x400). Pseudostratified cuboidal/columnar cells sitting on a basement membrane (black arrowhead). Mitotic figures (green arrowheads).
Inflammatory cells in lamina propria (blue arrowhead)

Slide Ref: 148/03 *

Colorectal polyps:

This is a benign, proliferative lesion, very common in middle-aged dogs, most commonly at the anorectal junction. Polyps frequently ulcerate leading to bleeding and local irritation. Excision is usually curative, but some may become invasive adenocarcinomas over time.

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