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The Seventeenth and Eighteenth Centuries:

In 1628, William Harvey published “Anatomica de Motu Cordis et Circulatione Sangunis in Animalibus” in which he outlined the circulation of the blood and the normal function of the heart. This was an enormous advance in medicine and pathology.

 

In this painting by Robert Hannah, William Harvey demonstrates his experiments on deer to King Charles I and the future King Charles II

 

The Italian Marcello Malpighi (1628-1694) expanded Harvey’s work. He discovered the capillaries and red blood cells and described the microscopic features of the kidneys, lungs and spleen.

The microscope revolutionised pathology. Hans and Zacharias Janssen of Holland are credited with the manufacture of the first microscope but it was almost immediately superseded by the superior instrument of Cornelius Drebbel of Holland. Another Dutchman, Antonj van Leeuwenhoek, popularised the use of microscopy.

 


Robert Hooke’s microscope as shown in an engraving from his Micrographica (1667).