Introduction

Lymphatic Invasion:

This route is favoured by most carcinomas, with the first metastases usually appearing within regional lymph nodes. Sarcomas may also occasionally spread via lymphatics.

Metastatic intestinal adenocarcinoma cells within lymphatic channels of the liver of a sheep.

Lymph node with extensive infiltration of subcapsular sinuses (SS) by tumour cells. LF = lymphoid follicle (x40)

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Lymphatic Invasion

Transplantation

Haematogenous Spread

Review Questions

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