Introduction
   

Case 4:

History:

Three 6 month old Merino weaners out of a flock of 500 died suddenly in good nutritional condition. The sheep were on dry pasture and fed 0.75 kg of oats twice weekly. At necropsy of one of the sheep, the liver was mildly swollen, mottled red-yellow, friable and tan discoloured, with a patchy zonal pattern. Fresh fibrin strands were present over the surface of the liver and between apposed liver lobes. There was mild oedema of the gall bladder and hilar connective tissues, petechiation of the gall bladder and a mild excess of clear yellow serous fluid in the peritoneal cavity.

 

In this low power view of the liver, much of the parenchyma appears redder than normal. A higher magnification will be needed to determine if this is congestion versus haemorrhage and necrosis. Portal areas are readily identifiable. Recognition of these is a useful first step in identifying the precise nature of zonal patterns of hepatic injury.

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