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Renal Infarct:
The cause of this infarct was a small emboli which had
lodged in the arterial supply to the local region of the kidney. These
lobular arteries supply a wedge shaped region of the medulla and cortex
as they support whole nephrons (Glomerulus to collecting duct). Obstructing
the arterial supply causes a wedge shaped area to become starved of blood
and appear pale. The hypoxia of the region results in coagulative necrosis
of the nephrons.
Inflammatory cells will slowly degrade the necrotic region and it would
be replaced by fibrous tissue if the animal was to survive. Inflammatory
cells require blood supply and therefore cannot enter into the necrotic
zone until small capillaries begin to grow in from the edges of the lesion.
 
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Veterinary
Pathology - Necrosis