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Introduction: Necrosis refers to a sequence of morphologic changes that
follow irreversible cell injury and cell death in living tissues (tissues
placed in fixative or frozen are dead but not necrotic). There are several
types of necrosis based on gross and histological appearance. General
characteristics of cell necrosis are pyknosis or loss of the cell nucleus,
hyper-eosinophilia of cell cytoplasm, loss of distinctive cell margins,
leading eventually to fragmentation of cells, or complete dissolution
of cells (ie lysis). In this practical you will be asked to examine, describe
and categorise different forms of necrosis and become familiar with recognising
necrotic cell in tissues. This intorduction should help to prepare you
for describing and diagnosing histopathological lesions.
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Veterinary
Pathology - Necrosis
