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Metastatic carcinoma
History:
A 10 year old cross bred dog presented with an acute onset
of tachypnoea (rapid breathing) without dyspnoea (difficulty in breathing). Weight loss and inappetence were also
noticed over the preceding 2 week period.
Embolic tumour cells within blood vessels (arrowheads)
(x40)
Slide ref: slide 1439/96 *
(x200)
Tumour cells are filling the lumens of these blood vessels.
Cells are large, with a large oval nucleus, and cells are closely adherent
(x400)
Metastatic carcinoma:
Many types of malignant tumours can metastasise to the
lungs. The most common are mammary carcinomas in dogs and cats, uterine
adenocarcinomas in cattle, and malignant melanoma in horses. Osteosarcomas,
fibrosarcomas and haemangiosarcomas are frequent varieties of sarcoma.
The presence of neoplastic cells within arteries is a good indication
of metastasis rather than the tumour being a primary lung tumour.
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