Introduction

Healing Wounds - 24hrs:

In both cases a fibrin clot forms (but this is much larger in secondary intention healing because of the larger tissue deficit), then neutrophils move in & line the margins of the wound. Basal cells begin to undergo mitosis in order to replace lost cells.
Between 24 & 48 hours epithelial cells from the wound edges begin to migrate & grow, depositing basement membrane as they move. They fuse in the midline beneath the surface scab, thus producing a thin but continuous epithelial layer. The time that elapses before this occurs depends on infection, size of deficit & sufficient blood supply.

Primary Intention

Second Intention

Review Questions

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