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Mesenchymal
Tumours:
Mesenchymal tumours typically exfoliate poorly and aspirates
may be non-diagnostic if the cell yield is poor. Most aspirated mesenchymal
cells are typically of small to medium size and spindloid shape with central
nuclei and polar cytoplasmic tails. With increasing grades of malignancy,
cell shape may become more polyhedral and less spindloid, nuclear and
nucleolar size increase and atypical mitoses may be observed.
Tumour cell morphology can vary greatly within the same
tumour mass. Classification of tumour types as epithelial, mesenchymal
or round is based on the dominant cell shape present.
This section of a mesenchymal tumour is composed of
spindle-shaped cells, with an elongated nucleus. Mitotic figures are uncommon.
(x400)
Same tumour as previous image. Tumour morphology can
vary marked throughout a mass. This area has very few spindle cells. Cells
are generally polygonal in shape, with occasional giant cells. (x400)
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