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Round
Cell Tumours:
Aspiration of round cell tumours usually yields numerous
discrete, round cells with distinct cytoplasmic margins. Round cell tumours
include mast cell tumours, histiocytomas, lymphomas, plasmacytomas and
multiple myelomas (both being neoplasms of B cells), and transmissible
venereal tumours. Sometimes, malignant melanomas and basal cell tumours
may also exfoliate cells as discrete round cells. Cytoplasmic granules
are diagnostic clues to the cell of origin in mast cell tumours, melanomas
and large cell granular lymphomas.
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