1. Arachidonic acid is formed primarily from HPETEs
(hydroperoxyeicosatetranoic acid) through the actions of phospholipase
A2 and phospholipase C
2. Cyclo-oxygenation of arachidonic acid leads to the
formation of leukotrienes, whereas lipoxygenation results in the formation
of prostaglandins of the I, F and E series and thromboxanes
3. Substances that are chemotactic for leukocytes include
complement colleague products derived from bacteria, cell components, and
specific products of arachidonic acid.
4. The primary granules of neutrophils contain not only
acid hydrolases, but also bactericidal cationic proteins, phospholipase
A2 and lysozyme.
5. The respiratory burst in activated leukocytes is
associated with an activation of the hexose-monophosphate shunt, increased
oxygen consumption, and superoxide formation.
Multiple Choice:
6. Choose from the following:
a. epithelioid cells
b. foreign body giant cell
c. both
d. neither
A. present in caseating granulomas
B. Present in foreign body granulomas
C. Derived from lymphocytes
D. Diagnostic of tuberculosis
E. May contain foreign material
7. Choose from the following:
a. granulation tissue
b. non-caseating granuloma
c. abscess
d. eosinophils
e. none of the above
A. Typical of parasitic infections
B. Contains pus
C. Typical of immune complex-mediated immune reactions
