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Benign cutaneous
histiocytoma:
History:
A small nodule was seen on the lower eyelid of a 2
year old staffy dog. The nodule was alopecic (hairless) and pink in colour (arrowhead).


Histological appearance of neoplastic round cells in
benign cutaneous histiocytoma. This neoplasm is derived from antigen-presenting
Langerhans cells of the epidermis.
Benign cutaneous histiocytoma:
These round cell tumours can occur at any age but are
most common in young dogs, especially on the face and ears. They are usually
circumscribed and alopecic masses (“button tumours”) which
commonly ulcerate. Typically, they grow rapidly and then spontaneously
regress after weeks to months due to a cell-mediated immune response involving
tumour infiltration by T lymphocytes.
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