Introduction

Haematoxylin & Eosin (x400)

Within the dermis, residual dermal collagen (DC) has a different histological appearance compared with granulation tissue (G) = fibroblasts, macrophages and new capillaries

Haematoxylin & Eosin

Trichrome stain

This stain highlights the immature collagen which is being laid down at the wound edges, between the normal dermal collagen and the granulation tissue of the wound. Newly deposited collagen stains blue in this section.

Primary Intention

Second Intention

Granulation Tissue

Review Questions

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